Phospho smad3
WebPhospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb recognizes endogenous levels of Smad2 protein when phosphorylated at Ser465 and Ser467. This … WebJul 1, 2012 · Smad3 is a critical intracellular mediator of TGFβ signaling regulated through phosphorylation by the TGFβ receptor complex at the C terminus. Smad3 is also a …
Phospho smad3
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WebPurity/Specificity. Anti-SMAD3 pT179 affinity-purified antibody is directed against the phosphorylated form of human Smad3 protein at the pT179 residue. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Antiserum was first purified against the phosphorylated form of the immunizing peptide. WebDec 30, 2024 · Phosphorylated forms (phospho-isoforms) in Smad-related pathways can transmit opposing signals: cytostatic C-terminally-phosphorylated Smad3 (pSmad3C) and carcinogenic linker-phosphorylated Smad3 (pSmad3L) signals.
WebAnti-phospho-Smad3 (Ser423/425) Antibody is a Rabbit Polyclonal Antibody for detection of phospho-Smad3 (Ser423/425) also known as MAD Mothers against DPP homolog 3 & has been validated in WB. Research Category Signaling. Quality. Evaluated by western blot on untreated and UV-treated AKR-2B cell lysate. WebJul 1, 2012 · Future studies will elucidate the impact of phospho-specific Smad3 signaling in the context of other TGFβ family members, including activin and Nodal, as well as other kinases and cancer models. Additionally, determining the differential function of Smad2 and Smad3 may be key to understanding the role of Smad signaling during carcinogenesis ...
WebThis antibody is phospho specific for dual phosphorylated pS423 and pS425 of Smad3. Stimulation with 2 ng/ml TGF-beta for 1 hour is suggested. Purity/Specificity. This affinity … WebMar 21, 2024 · SMAD3 (SMAD Family Member 3) is a Protein Coding gene. Diseases associated with SMAD3 include Loeys-Dietz Syndrome 3 and Aortic Aneurysm, Familial …
WebSMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. …
philosopher\u0027s stone table ffxivWebThis antibody is phospho specific for dual phosphorylated pS423 and pS425 of Smad3. Stimulation with 2 ng/ml TGF-beta for 1 hour is suggested. Purity/Specificity This affinity-purified antibody is directed against the phosphorylated form of human Smad3 protein at the pS423 and pS425 residues. philosopher\u0027s stone tbc wowWebSmad3 (also known as Mothers against decapentaplegic homolog 3, Mothers against DPP homolog 3, Mad3, hMAD-3, JV15-2 or hSMAD3) is a transcriptional modulator activated by … philosopher\u0027s stone symbol meaningWebDescription Rabbit polyclonal to Smad2 + Smad3 (phospho T8) Host species Rabbit Tested applications Suitable for: WB more details Species reactivity Reacts with: Mouse, Human Predicted to work with: Rat Immunogen Synthetic peptide corresponding to Human Smad2 + Smad3 (phospho T8). philosopher\\u0027s stone tableWebSmad3 and phospho-Smad3 are potential markers of invasive nonfunctioning pituitary adenomas Chunhui Liu,1,2 Zhenye Li,1–3 Dan Wu,4 Chuzhong Li,1–3 Yazhuo Zhang1–3 … philosopher\\u0027s stone symbolWebApr 7, 2024 · Moreover, deletion of Smad3 from db/m or db/db mice almost competitively blocked SARS-CoV-2 N-induced Ripk3/MLKL expression and phospho-MLKL level (Fig. … t shirt alleyWebPhospho-Smad3 (S423/S425)/Smad2 (S465/S467) Cell-Based ELISA Summary. Alternatively. * Alternatively, this assay can be run over two days, which requires 2 hours … t shirt all blacks