WebJan 15, 2024 · PHF10 is a subunit of the signature module of PBAF, responsible for its interaction with chromatin. PHF10 is represented by four different isoforms, which are alternatively incorporated in the complex. Two of PHF10 isoforms lacking C-terminal PHD domains contain a cluster of phosphorylated serine residues, designated as X-cluster. WebБәхәс:PHF10. Бәхәс. : PHF10. Бу мәкалә тематикасы «Биология» википроекты белән бәйле. Аның максаты — темалары буенча Биология белән бәйле мәкаләләрне төзү һәм яхшырту. Теләсәгез, мәкалә өстендә ...
PHF10 subunit of PBAF complex mediates transcriptional …
WebAnti-PHF10 antibody (ab154637) Datasheet SDS Submit a review Submit a question References (3) Key features and details Rabbit polyclonal to PHF10 Suitable for: WB, IHC-P, ICC/IF Knockout validated Reacts with: Mouse, Human Isotype: IgG You may also be interested in Protein Recombinant Human PHF10 protein (ab127369) WebDec 1, 2024 · The PHF10 is the most unstable subunit of PBAF and its isoforms demonstrate different stability in the complex, depending on their domain structure. Their stability is regulated by the CK-1 multiple phosphorylation cluster which protects PHF10 from the b-TrCP ubiquitin ligase-dependent degradation [ 17 ]. children first internet class
FGF10 - an overview ScienceDirect Topics
WebApr 1, 2024 · Here we provide evidence that BAF45a/PHF10, a subunit of SWI/SNF-like chromatin remodeling complexes, is essential for adult hemopoietic stem cell maintenance and myeloid lineage development. Deletion of BAF45a in the mouse is embryonic lethal. WebApr 1, 2024 · PHF10 loss-of-function resulted in elevated recruitment of γH2AX, RAD51, and 53BP1 to DSB sites and decreased HR repair efficiency. Moreover, ZC3H13 knockdown downregulated the m 6 A methylation of PHF10 and decreased PHF10 translation in a YTHDF1-dependent manner. WebOct 21, 2024 · We revealed a disease progression associated elevation of PHF10 subunit of PBAF in clinical melanoma samples. In melanoma cell lines, PHF10 interacts with MYC … children first learning center waco